The Vienna Doctoral School in Chemistry offers 17 fully funded PhD positions to be filled between early summer and end of 2024

 

According to the university's recruitment policy, all advertised positions are available for 3 years with different options for extension. The contract is subject to approval after 1 year. The University of Vienna and DoSChem pursue a non-discriminatory employment policy and value equal opportunities, as well as diversity.

Expectations for successful candidates

We expect the successful candidate to sign a doctoral thesis agreement within 12 months after starting the appointment and participation in teaching as defined by the collective agreement. Further, we expect the successful candidate to be able to work in a team, supervise students, participate in the organization of symposia, and present results in publications and at international conferences.

The language of the school is English; therefore, English is required, and German is an advantage. Further expectations are:

•    Strong communication, data presentation, and visualization skills
•    Ability to work both, independently and collaboratively
•    Involvement in the institute’s research administration and teaching activities

 

overview of the open positions

click on the link to get directly the coresponding project description

  • Institute of Analytical Chemistry (1 position)
  • Institute of Biological Chemistry   (2 positions)
  • Institute of Biophysical Chemistry (3 positions)
  • Institute of Computational Biological Chemistry and Food Chemistry and Toxicology         (1 position)

 

 

 

 

 

 

  • Institute of Structural and Computational Biology/Max Perutz Labs (1 position)
  • Institute of Inorganic Chemistry (1 position)

Analytical Chemistry

#1 PhD position in AI in Bioprocess Modeling

A PhD position is available in the group of Prof. Zanghellini at the Institute of Analytical Chemistry, starting spring of 2024 or later. In this project, the successful PhD candidate will pioneer the development of AI-based tools for optimizing biotechnological production processes. Leveraging time course data enhanced with AI technology, the candidate will create precise bioprocess models through parameterization and characterization. These models will subsequently be employed to predict and implement optimal process designs. Information about the group Biochemical Network Analysis can be found here: https://chemnet.univie.ac.at/ 

Your tasks:

  • Apply Statistical Methods: utilize statistical methods to analyze high-dimensional datasets associated with bioprocesses
  • Implement AI-Based Tools: develop and implement AI-based tools for the characterization of bioprocesses
  • Integration into Optimization Workflows: integrate developed process models into existing optimization workflows, enhancing their performance
  • Predict Optimal Process Designs: utilize the integrated models to predict optimal process designs for biotechnological production
  • Collaborative Implementation: collaborate with experimentally working partners to implement the predicted optimal process designs

Your profile:

  • Master of Science (Bio-)Data Science / Bioinformatics / Molecular Bio(techno)logy / Biochemistry / Informatics or similar
  • Strong programming skills
  • Experience in statistics and handling of multi-dimensional datasets
  • Familiarity with machine learning libraries is a plus
  • An additional advantage with experience in metabolic modeling

Biological Chemistry

#2 PhD position in Biological Chemistry

A PhD position is available in the group of Prof. Becker, at the Institute of Biological Chemistry, starting date between July and October 2024. The Becker group combines chemical approaches, such as the synthesis of modified amino acids with solid phase peptide synthesis (SPPS), and biotechnological methods such as protein expression to address scientific challenges in the areas of protein biochemistry, biomaterials, and biomedicine. Information about the group can be found at: https://biologischechemie.univie.ac.at/en/research/becker/

Your tasks:

  • Synthesis of modified peptides and expression of proteins
  • Assembly of functionalized materials based on biomimetic processes
  • Analysis of peptides, biomolecules and biomaterials
  • In vitro studies of proteins and functionalized materials
  • Participation in conferences
  • Preparation of publications/posters/presentations
  • Supervision of students

Your profile:

  • Diploma or master's degree in Chemistry or Biochemistry or closely related fields
  • Experience in the area of peptide and protein chemistry with materials chemistry
  • Strong communication, writing, and data presentation skills in English
  • Ability to work both independently and collaboratively

#3 PhD position in Chemical Biology and Neuropeptide Research

A PhD position is available in the group of Prof. Muttenthaler at the Institute of Biological Chemistry towards the end of 2024. Neuropeptides are key mediators in many biological functions and understanding their interaction with target proteins is fundamental to unraveling the underlying mechanism of diseases. Over the years, an increasing number of bioactive peptides from animals, plants, and bacteria have been characterized, with the overwhelming realization that these molecules often show better therapeutic performance than their human counterparts, particularly in terms of in vivo stability.                 

Our main research efforts situated in this area of Chemical Biology focus on the exploration and translation of these vast and untapped natural libraries towards the development of useful research tools and therapeutics. Solid-phase peptide synthesis, the main tool to access these compounds, is a powerful technology for the assembly and chemical modification of these highly chiral and structurally complex peptides. We then use these ligands to develop advanced molecular probes and therapeutic leads to address important questions of unmet medical needs.

Information about the groups can be found here: https://www.neuropeptidelab.com/

Your tasks:

  • Chemical synthesis
  • Biophysical characterization of molecules
  • Recombinant protein expression
  • Pharmacological assays
  • Phenotypic bioassays/screens
  • Cell culture
  • MS, HPLC, NMR, CD

Your profile:

  • Masters/Honors in Chemistry, Pharmacology, Chemical Biology, Biochemistry or related discipline
  • Strong chemistry, pharmacology, or molecular biology background
  • Strong ambition and good work ethics

Biophysical Chemistry

#4, #5 and #6 PhD positions in the area of synthesis, characterization, and investigation of polyoxometalates

In the group of Prof. Rompel at the Institute of Biophysical Chemistry following 3 PhD positions are available anytime starting the summer of 2024 and later. Information about the group can be found here: https://www.bpc.univie.ac.at

Your tasks:

  • #4 Activation of a type 3 copper protein
  • #5 Synthesis and characterization of a polyoxometalate
  • #6 Isolation and characterization of a type 3 copper protein

Your profile:

  • Completed degree (Master, Graduate Engineer) in Chemistry, Biochemistry, Biotechnology, Molecular biology, Physics, or similar
  • Good knowledge of German

Computational Biological Chemistry /Food Chemistry and Toxicology

#7 PhD position in the project “from virtual to vital“: integrating computational and experimental approaches to unravel the activity of bacterial metabolites on the bladder epithelium

A joint PhD position is available in co-supervision of Prof. Schröder at the Institute of Computational Biological Chemistry and Assoc.- Prof. Del Favero at the Institute of Food Chemistry and Toxicology starting ASASP or anytime soon. Urinary tract infections are painful diseases prone to chronic occurrence. Zooming from molecular interaction up to cellular response pathways, this project aims to explore the complex relationships between urinary microbial communities and bladder cells. With the combination of in silico modeling experimental toxicology and microbiology, we propose to gain unprecedented insights into the adaptive plasticity of bladder cells and shed light on their capacity to modulate their function in response to bacterial and dietary metabolites in the genitourinary tract. Information about the groups can be found here: https://biophysical-toxicology.univie.ac.at/   and  www.mdy.univie.ac.at/index.html

Your tasks:

  • Use molecular dynamics simulations to explore the interaction between the molecules of bacterial origin and mammalian cells
  • Establish a complex cell culture model of bladder cells to verify the hypothesis generated during the in-silico screening
  • Integrate research with the collaboration partners at the Institute of Microbiology and Ecosystem Science-DoME

Your profile:

  • Master of Science in Chemistry, Molecular Biology, Pharmacy, or related fields
  • Affinity for both computational and experimental work
  • Fluent communication (oral and written) in English and German

Food Chemistry and Toxicology

#8 PhD position in Food Chemistry and Exposomics

A PhD position is available in the group of Prof. Warth, at the Institute of Food Chemistry and Toxicology, starting June 2024 or later. 

The 'Global Exposomics and Biomonitoring Laboratory' consists of a dynamic, collaborative team acting in a strong interdisciplinary network. We explore the impact of food- and environment-related toxicants on human health using innovative methods to investigate exposure, metabolism, and toxicity. Information about the group can be found here: exposomics.univie.ac.at

Your tasks:

  • Develop mass spectrometry-based assays and evaluation methods for exposome research and metabolomics 
  • Apply innovative mass spectrometry-based workflows to address interdisciplinary research questions bridging biomedicine, microbiome, and environmental research 
  • Participate in collaborative research projects, teaching, and some administrative tasks

Your profile:

  • MSc degree in Analytical, Biological, Food, or Computational Chemistry, Biotechnology or related field
  • Experience in mass spectrometry and/or advanced programming skills and statistical knowledge 
  • Scientific publishing experience is an asset, excellent written and oral communication skills as well as strong organizational skills are required
  • High level of self-motivation, commitment, and work ethic; willingness to travel and manage cooperative projects

#9 PhD position in Food Toxicology

A PhD position is available in the group bioactivity and molecular mechanisms under the supervision of Prof. Marko, at the Institute of Food Chemistry and Toxicology, starting September 2024.  The dynamic interdisciplinary team (https://lmc.univie.ac.at/), engaged in a network of national and international collaborations, boasts solid expertise in research on the toxicity of mycotoxins. One current research focus involves studying the toxicity of precursors of the carcinogenic mycotoxin “aflatoxin B1” and assessing their potential impact on human health. Additionally, special attention is devoted to unraveling the mechanisms behind the toxic effects exerted by mycotoxins.

Your tasks:

  • Assessment of the toxic effects of aflatoxin B1 precursors.
  • Investigation of the mechanisms of toxicity in human cells.

Your profile:

  • Master of Science (Chemistry, Food Chemistry, Biology, Pharmacy, Nutritional Sciences or comparable)
  • Experience with analytical-chemical and toxicological methods, including cell culture work, is advantageous

Functional Materials and Catalysis

#10 PhD position in Organometallic Chemistry/Catalysis

A PhD position is available in the group of Prof. Hultzsch, at the Institute of Functional Materials and Catalysis, starting November/December 2024 or later. The project deals with the synthesis and characterization of homogeneous base metal complexes and their application in catalytic reactions, such as borrowing hydrogen processes. The investigations are accompanied by mechanistic and kinetic studies of the catalytic reactions. Information about the group can be found here: https://chemcat.univie.ac.at/

Your tasks:

  • Synthesis and characterization of transition metal complexes
  • Investigations of catalytic processes and characterization of the organic products
  • Investigation of reaction mechanisms via spectroscopic and kinetic studies

Your profile:

  • Master of Science (Chemistry)
  • Experience with organic synthetic and analytical methods
  • Experience in the synthesis and characterization of homogeneous organometallic compounds, including working under an inert atmosphere (Schlenk line, glove box) is desired

Organic Chemistry

#11 PhD position in Synthetic Organic Chemistry

A PhD position at the Institute of Organic Chemistry is available starting fall of 2024 and later. Information about the institute can be found here: orgchem.univie.ac.at/en/

Your tasks:

  • Development of new organic synthetic methods
  • Organic synthesis of valuable products
  • Synthetic organic methodology

Your profile:

  • Applicants must hold a 1st Class Honors degree (or equivalent) in Organic Chemistry by the time of the appointment
  • Only candidates with a Master's degree with a strong theoretical and practical background in the field of organic synthesis/chemistry will be considered
  • Experience in heterocyclic chemistry could be regarded as an added value
  • Very good spoken and written English is also mandatory

#12, #13, #14, and #15 PhD positions in Organic Chemistry

In the group of Prof. Bonifazi at the Institute of Organic Chemistry following 4 PhD positions are available anytime from fall 2024. Information about the group can be found here: https://bonifazi-group.univie.ac.at/

#12 Green Chemistry: project sponsored by FFG in collaboration with BASF about the development of organic-based photo and electrocatalytic approaches to induced depolymerization of relevant plastics.

Your tasks:

  • Development of electrochemical and photochemical procedures tackling the depolymerization reaction of common organic polymers
  • Organic synthesis of photoelectrocatalysis
  • Application for the depolymerization protocols on real materials and recycling of the monomers

Your profile:

  • Applicants must hold a 1st Class Honors degree (or equivalent) in Chemistry with a specialization in Organic Chemistry by the time of the appointment
  • Only candidates with a Master's degree with a strong theoretical and practical background in the field of organic synthesis will be considered.
  • Experience in heterocyclic chemistry could be regarded as an added value.

 

#13 Physical Organic Chemistry

Your tasks:

  • Electrochemical and photochemical characterization of organic chromophores
  • Development of new light-harvesting antenna materials for energy conversion applications
  • Physicochemical investigations of photocatalytic processes

Your profile:

  • Applicants must hold a 1st Class Honors degree (or equivalent) in Chemistry with specialization in Physical and Material Chemistry by the time of the appointment
  • Only candidates with a Master's degree with a strong theoretical and practical background in the field of spectroscopy will be considered. Experiences with typical absorption and emission UV-vis-NIR spectroscopy techniques will be regarded as an added value.

 

#14 PhD position in Synthetic Organic Chemistry & #15 PhD position in Synthetic Organic Chemistry and Cluster of Excellence

Your tasks:

  • Development of new sustainable organic synthetic procedures targeting the formation of C-C and C-Het bonds
  • Organic synthesis of precursors
  • Targeted-oriented synthesis of functional molecules for applications in optoelectronic (#14)
  • Targeted-oriented synthesis of functional molecules for applications in light harvesting (#15)

Your tasks:

  • Applicants must hold a 1st Class Honors degree (or equivalent) in Chemistry with a specialization in Organic Chemistry by the time of the appointment 
  • Only candidates with a Master's degree with a strong theoretical and practical background in the field of organic synthesis will be considered. 
  • Experience in heterocyclic chemistry could be regarded as an added value.
  • For all applicants for Organic Chemistry positions: very good spoken and written English is also mandatory (mandatory IELTS score = 6.5).

Department of Physical Chemistry

#16 PhD position in Physical Chemistry

A PhD position is available in the group of Prof. Backus, at the Institute of Physical Chemistry, starting any time soon. The position is devoted to the use of advanced spectroscopic experiments to study complex systems relevant to atmospheric chemistry and/or catalytic reactions with a focus on surface phenomena. Information about the group can be found at: https://pchem.univie.ac.at/en/research-groups/ultrafast-and-nonlinear-spectroscopy/


Your tasks:

  • Performing and analyzing complex spectroscopic experiments
  • Presenting the results in publications and at conferences

Your profile:

  • MSc degree in Physical Chemistry, Physics, or a related field 
  • Experience with (vibrational) spectroscopy and/or optics would be an advantage

Institute of Structural and Computational Biology

#17 PhD position in Structural Biology of RNA metabolism

A PhD position is available in the group of Assoc.-Prof. Falk, at the Max Perutz Labs, Institute of Structural and Computational Biology starting August 2024 or later. The project deals with the structural and biochemical characterization of proteins and protein complexes involved in regulating gene expression and RNA metabolism. Information about the group can be found here: https://www.falklaboratory.org/

Your tasks:

  • Purification & reconstitution of multiprotein complexes involved in RNA metabolism
  • Investigation of the protein-protein interactions and the regulation of the enzymatic activities within the complex
  • Structural characterization (X-ray crystallography & cryo-EM) of the proteins and protein complexes to obtain mechanistic insights

Your profile:

  • Master of Science (Biochemistry, Chemistry or Biology)
  • Experience with producing and purifying proteins and protein complexes and characterizing protein-protein interactions and enzymatic activities
  • Basic knowledge in the area of structural biology 


Institute of Inorganic Chemistry

# 18 PhD position in Bioinorganic Radiochemistry

A PhD position is available in the Bioinorganic Radiochemistry group of Assoc. Prof. Mindt, at the institute of Inorganic Chemistry, starting approx. June 2024. Information about the group can be found here: (https://mindt-group.univie.ac.at/).

The project aims at the development of novel radiopharmaceuticals for diagnostic (imaging) and therapeutic applications in nuclear medicine. Chelators will be synthesized and coupled to a tumor-targeting (bio)molecule (e.g., peptides). In solution synthetic chemistry and solid phase assisted chemistry will be part of project. Subsequently, the conjugates will be labelled with metallic radioisotopes and evaluated preclinically in vitro (on cells) and in vivo (mice).

Your tasks:

  • Synthesis of chelators and their bioconjugation to molecules of medicinal interest
  • Radiolabeling of peptide conjugates and quality control (e.g., HPLC), and stability tests etc.
  • Preclinical evaluation of radiolabeled conjugates

Your profile:

  • Master of science (chemistry, pharmacy or equivalent)
  • Experience in synthetic organic/inorganic/peptide chemistry and analytical methods (MS, NMR)
  •