Apply@DoSChem

The DoSChem Call opens on March 15th, 2021 (Deadline May 16th, 2021). In order to apply, register yourself at the University of Vienna and open an U: account first. With your u:account User ID you can apply@doschem.

 

 

Expectation for successful candidates

We expect the successful candidate to sign a doctoral thesis agreement within 12 months after starting the appointment and participation in teaching as defined by the collective agreement. Further, we expect the successful candidate to be able to work in a team, supervise students, to participate in the organization of symposia, present results in publications and at international conferences.

Open Positions:

#1 - PhD position in Medicinal Chemistry/ Bioinorganic Chemistry

In the group of Prof. Kowol at the Institute of Inorganic Chemistry a PhD position is available from October 1st, 2021. The project will be carried out as part of the “Translational Cancer Therapy Research” cluster in close cooperation with the Institute for Cancer Research at the Medical University of Vienna.

Your tasks:

  • Implementation of research projects with a strong focus on the synthesis and characterization of novel anticancer (metal) compounds and their (bio)analytical investigation.

Your profile:

  • Completed diploma or master’s degree in chemistry, preferably in the field of synthetic chemistry or an equivalent qualification.
  • Experience in the synthesis of biologically active compounds as well as in the field of analytical and preparative HPLC.

#2 - PhD position in Analytical Chemistry

In the group of Prof. Ahrends at the Institute of Analytical Chemistry, a PhD position is available starting fall 2021. The group is seeking a talented and highly motivated scientist to pursue mass spectrometry based quantification experiments to elucidate novel signaling hubs in cellular stress pathways to investigate cellular plasticity and adaptation. The primary focus is the development and implementation of tools suited for multi-omics workflows with a strong proteomics focus and in the context of cardiovascular research.

Your tasks:

  • Develop of targeted mass spectrometry workflows to investigate signaling pathway.
  • Complement available data bases.
  • Integrate your findings with other omics-strategies.

Your profile:

  • Master of science (chemistry, biology or similar), with a publication record.
  • A solid understanding of the relevant concepts in mass spectrometry and proteomics.
  • An understanding of the statistical principles behind current best practices in the field.
  • Ability to work both independently and collaboratively, and to handle several concurrent projects.

#3 - 2 PhD positions in Physiological Chemistry

At the Institute of Physiological Chemistry in the group of Dr. Lieder and in the group of Prof. Grune 2 PhD positions are available starting fall 2021 (Lieder, position 1)  and the first quarter of 2022 (Grune, position 2).

The projects will be carried out in collaboration with the German Institute of Human Nutrition, Potsdam, Germany and the Leibniz Institute for Food Systems Biology, Freising, Germany. More information about the group can be found here.

Your tasks:

  • Work in an interdisciplinary and international team to perform studies on the identification of the signaling pathways of bioactive food ingredients (position 1) or the analysis of food composition (position 2) via application of state-of-the-art molecular biological, biochemical, and analytical techniques.
  • Participation in animal studies.
  • Participation in proof-of-concept human intervention studies.

Your profile:

  • Master degree in biological chemistry, nutrition, food chemistry or related field.
  • Hands-on experience in cell culture techniques.
  • Hands-on experience in molecular biological (PCR, sequencing, gene editing) and biochemical methods (photometrical assays, Western Blot, ELISA) (position 1).
  • Hands-on experience in analytical chemistry (LC-MS, GC-MS) (position 2).

#4 - 2 PhD positions in Physical Chemistry

In the group of Prof. Backus at the Institute of Physical Chemistry 2 PhD positions are available from fall 2021. The two position are devoted to perform time resolved and multidimensional spectroscopy on environmental relevant systems. Information about the group can be found here.

Your tasks:

  • Performing and analyzing complex spectroscopic experiments.

Your profile:

  • Master degree in physical chemistry, in physics or in a related field.
  • Experience with (vibrational) spectroscopy and/or optics would be an advantage.

#5 - PhD position in Biological Chemistry

In the group of Prof. Becker at the Institute of Biological Chemistry a PhD position is available from fall 2021. Information about the group can be found here

Your tasks:

  • Synthesis of modified peptides and expression of proteins.
  • Assembly of proteins by chemoselective ligations.
  • Analysis by mass spectrometric and biochemical characterization.

Your profile:

  • Diploma or master degree in Chemistry or Biochemistry or closely related fields.
  • Experience in the area of peptide and protein chemistry, such as peptide synthesis and selective protein modification and/or with protein expression and characterization of proteins.

#6 - PhD position in Inorganic Chemistry - functional Materials

In the group of Prof. Kleitz at the Institute of Inorganic Chemistry – Functional Materials a PhD position is available starting January 2022. Information about the group can be found here

Your tasks:

  • Synthesis of nanostructured metal oxides and hybrids.
  • Characterization of the structure, surface and porosity of the (nano)materials.
  • Investigation of the electrocatalytic properties.

Your profile:

  • Diploma or Master degree in Chemistry or Chemical Engineering or closely related fields.
  • Knowledge in electrochemistry and catalysis.
  • Some experience in the area of nanostructured metal oxides, and their use in heterogeneous catalysis and/or energy storage systems.

#7 - PhD position in organic synthesis of heterocycles for engineering chalcogen-bonding recognition frameworks

In the group of Prof. Bonifazi at the Institute of Organic Chemistry a PhD position is available anytime from September 2021. Information about the group can be found here

Your tasks:

  • Development of organic synthetic procedures for preapring heteorcyclic frameworks bearing one or more S-, Se- or Te atoms at theirs peripheries.
  • Engineering of programmable of chalcogenide scaffolds featuring simultaneous expression of three and four chalcogen-bonding interactions.
  • Physical organic chemistry studies to investigate the strength and selectivity of chalcogen bonding-driven assotiation in solution.
  • Design of functional polycylic aromatic hydrocarbons that, through the use of chalcogen-bonding interactions, can undergo self-assembly to form supramolecular 2D semiconductors.

Your profile:

  • Applicants must hold a Master degree (or equivalent) in Chemistry with specialization in Organic Chemistry by the time of the appointment.
  • Only candidates with a Master degree with a strong theoretical and practical background in the field of organic synthesis will be considered. Experience in heterocyclic chemistry could be regarded as an added value.
  • Very good spoken and written English is also mandatory (mandatory IELTS score = 6.5).

#8 - PhD position in Stereoselective Synthesis and Catalysis

In the group of Prof. Maulide at the Institute of Organic Chemistry a PhD position is available starting fall 2021. Information about the group can be found here.

Your tasks:

  • Stereoselective Synthesis and Catalysis.
  • Natural Product Synthesis.
  • Reaction Development.

Your profile:

  • Organic Synthesis.
  • Mechanistic Understanding (Organic Chemistry).
  • Interpretation of Spectroscopic Data (NMR, HRMS).
  • Working under Inert Atmosphere/Schlenk Technique.

#9 - PhD position in computational metabolomics

In the group of Prof. Zanghellini at the Institute of Biochemical Network Analysis, Department of Analytical Chemistry a PhD position is available starting fall 2021 or sooner.

Project description

In this project the successful PhD candidate will extend the portfolio of software for the annotation/identification of unknown natural product metabolites with machine learning techniques and/or neural networks. On the basis of similarities in MS/MS spectra, molecular networks and machine learning, these tools shall generate putative and plausible chemical structure candidates. For more information, please visit here.https://ucloud.univie.ac.at/index.php/s/MwdMKzWkINlwddj

Your tasks

  • Comparison and integration of existing tools into a comprehensive workflow/toolkit.
  • Mine publicly available datasets for high-quality MS/MS spectra/information to be used for training machine learning models.
  • Development of statistical/machine learning methods/tools for annotation/generation of unknown metabolite structures.
  • Integration of the novel software tool(s) with existing software for in-silico metabolite identification/characterization.
  • Application of developed data processing approaches.

Your profile

  • Diploma or master degree in Cheminformatics/Bioinformatics/Statistics/Informatics.
  • Statistics, clustering techniques, dealing with high-dimensional datasets, machine-learning.
  • High level programming skills.
  • Experience with machine learning libraries is considered a plus.
  • Experience with Mass Spectrometry is considered a plus.

#10 - PhD position in DNA methylation analysis

In the group of Prof. Cichna-Markl at the Institute of Analytical Chemistry a PhD position is available starting January 2022. Information about the group can be found here

Your tasks:

  • Development and validation of methods (based on high resolution melting analysis, pyrosequencing) for DNA methylation analysis at regulatory elements (promoters, enhancers) of ATP binding cassette (ABC) transporters.
  • Investigation of the role of aberrant DNA methylation of ABC transporters in cancer.
  • Investigation of the applicability of aberrant DNA methylation of ABC transporters as diagnostic, prognostic and/or predictive biomarker in cancer.

Your profile:

  • Master´s Degree in Chemistry, Biochemistry, Molecular Biology or related subjects.
  • Profound knowledge in analytical chemistry.
  • Basic knowledge in statistics.
  • Basic knowledge of molecular biological techniques.

#11 - PhD position in theoretical and computational chemistry

In the group of Prof. González at the Institute of Theoretical Chemistry a PhD position is available starting fall 2021.

Your tasks:

  • The successful candidate will work  within the collaboratory network Catalight (www.catalight.eu), a project  with the goal of designing molecular components embedded in soft materials for artificial photosynthesis.

Your profile:

  • Master degree in Chemistry.
  • Experience in the area of quantum chemistry is a must.
  • A good background in organic and inorganic chemistry, molecular dynamics and light-induced processes.
  • Programming skills of advantage.

#12 - PhD position in Chemical Biology and Neuropeptide Research

In the group of Prof. Muttenthaler at the Institute of Biological Chemistry a PhD position is available from second half of 2021/start of 2022. Information about the group can be found at here.

Project description

Neuropeptides are key mediators in many biological functions and understanding of their interaction with target proteins is fundamental to unravel the underlying mechanism of diseases. Our main research efforts focus on the exploration and translation of these vast and untapped natural libraries towards the development of useful research tools and therapeutics. Solid phase peptide synthesis, the main tool to access these compounds, is a powerful technology for the assembly and chemical modification of these highly chiral and structurally complex peptides. We then use these ligands to develop advanced molecular probes and therapeutic leads to address important questions of unmet medical need.

Your tasks:

  • Chemical synthesis.
  • Biophysical characterization of molecules.
  • Recombinant protein expression.
  • Pharmacological assays.
  • Phenotypic bioassays/screens.
  • Cell culture.
  • MS, HPLC, NMR, CD.

Your profile:

  • Master in chemistry, pharmacology, chemical biology, biochemistry or related discipline.
  • Strong chemistry, pharmacology or molecular biology background.
  • Strong ambition and good work ethics.

#13 - PhD position in Bioinorganic Chemistry

In the group of Prof. Keppler at the Institute of Inorganic Chemistry a PhD position is available from October 1st, 2021. The project will be carried out as part of the “Translational Cancer Therapy Research” cluster in close cooperation with the Institute for Cancer Research at the Medical University of Vienna. Information about the group can be found here

Your tasks:

  • Strong focus on the synthesis and characterization of novel organometallic anticancer compounds and their (bio)analytical investigation.

Your profile:

  • Diploma or master’s degree in chemistry, preferably in the field of synthetic chemistry or an equivalent qualification.
  • Experiences in the field of synthetic chemistry, especially the synthesis and characterization of metal complexes.